THE POTENTIAL ROLE OF NOS1 G-84A POLYMORPHISM IN IGA VASCULITIS

Authors

  • Robiyaxon Baxodirova Author
  • Mahliyo Berdiqobilova Author
  • Azizbek Jakhonov Author

Keywords:

NOS1 G-84A, G-84A variant, vascular pathology, metabolism and endothelial dysfunction

Abstract

Immunoglobulin A vasculitis (IgAV) is a systemic small-vessel vasculitis characterized by vascular inflammation and endothelial injury. Nitric oxide (NO) is an important regulator of vascular tone and endothelial function. The NOS1 gene encodes neuronal nitric oxide synthase (nNOS), which contributes to NO production in different tissues. Genetic variation in NOS1 may influence NO-dependent vascular regulation

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Published

2026-09-11

Issue

2026: LOCAL-REGIONAL RELAPSES AND METASTASISES AS THE FACTORS OF LIMITING OF SURVIVAL RATE OF WOMEN WITH BREAST CANCER

Section

Articles